This project aims at understanding pig immune system for food production and translation research. This will provide an immune cell atlas as a basis for future research. Moreover, it will improve cell type and tissues specific gene expression data for genetic selection.
Immune tissues were collected from two 6 month old healthy pigs. Created clusters of single cell data and proved they are unique and distinguishable. Identified gene expression patterns and markers for different immune cell types. Identified tissue specific vs. peripheral immune cell types by comparing against porcine PBMCs Identified tissue-specific differences between porcine and human cell types. Used canonical markers, porcine PBMC data and human tissue-specific data to annotate the porcine immune cell atlas.
Gene Expression for Single Cell Immune Tissues
Developed by
Tuggle Lab
VISUALIZATION OF GENES
The Integrated Seurat object of Four Tissues: